Disorder of Hemoglobin : Genetics, Pathophysiology, and Clinical Management, 2nd ed, 2009,

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Disorder of Hemoglobin Genetics, Pathophysiology, and Clinical Management

Martin H. Steinberg, Bernard G. Forget, Douglas R. Higgs, David J. Weatherall.

ISBN-13 978-0-521-87519-6

ISBN-13 978-0-511-59618-6 [ebook]

Cambridge University Press

To date, more than 1,000 hemoglobin variants have been discovered and characterized. Study of these variants, so amply documented in this book, established the principle of how a mutant genotype alters the function of the protein it encodes, which in turn can lead to a distinct clinical phenotype.

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